A cozy hotel room featuring a bed, sofa, coffee table, lamps, wall art, and a view into a bathroom and kitchenette area.
A small outdoor swimming pool with metal ladders, surrounded by a fence, and patio tables with umbrellas near a building.

Apartment-Style Living

A Texas Medical Center Hotel Houston

Our MainStay Suites® Texas Medical Center offers guests apartment-style accommodations so they have the comforts of home while they’re away. We offer extended stay options for guests who are visiting Houston for a long stay. Our hotel is conveniently located to the Texas Medical Center. We offer free shuttle service to the medical center as well as other sites within a 3 mile radius.

A hotel reception area with a long counter, overhead lights, and a painting on the wall. The floor is tiled, and the area is well-lit.
A cozy living area with tables, chairs, a TV, bookshelf, sofas, and decor in a room with large windows and tile flooring.
A hotel reception area with a long counter, overhead lights, and a painting on the wall. The floor is tiled, and the area is well-lit.
A cozy living area with tables, chairs, a TV, bookshelf, sofas, and decor in a room with large windows and tile flooring.
A hotel room featuring two double beds with patterned comforters, a bedside lamp, wall art, and a closet with hangers in the corner.
A hotel room with a bed, two bedside tables, lamps, and a framed picture above the headboard. The room has a warm and cozy atmosphere.

Stay Longer, Live Better

Rooms & Suites

Experience comfort and versatility in our residential-style suites at MainStay Suites Texas Medical Center/Reliant Park. Each of our 89 spacious rooms features a fully equipped kitchen, separate living and work areas, free high‑speed Wi‑Fi, and a safe with workspace—ideal for both business travelers and families.

See Rooms

This image shows a gym with various fitness equipment, including treadmills, exercise bikes, and a multi-station workout machine.
A person in a cafe is stirring a drink while using a laptop, with notebooks and a smartphone on the table.

Amenities & Services

At MainStay Suites Texas Medical Center/Reliant Park, enjoy thoughtful amenities designed for extended comfort and convenience. Whether you're in Houston for business, medical visits, or a long-term stay

Amenities

Specials & Packages

Make the most of your stay with special deals designed to add value and comfort. Whether you're booking a quick getaway, an extended stay, or a business trip, our Houston hotel offers provide discounted rates

See Offers

This image shows a gym with various fitness equipment, including treadmills, exercise bikes, and a multi-station workout machine.

Amenities & Services

At MainStay Suites Texas Medical Center/Reliant Park, enjoy thoughtful amenities designed for extended comfort and convenience. Whether you're in Houston for business, medical visits, or a long-term stay

Amenities

A person in a cafe is stirring a drink while using a laptop, with notebooks and a smartphone on the table.

Specials & Packages

Make the most of your stay with special deals designed to add value and comfort. Whether you're booking a quick getaway, an extended stay, or a business trip, our Houston hotel offers provide discounted rates

See Offers

A kitchenette with wooden cabinets, appliances, a lamp on a desk, a chair, and a window with curtains is shown.
The image shows a U-shaped conference room setup with tables and chairs, a podium, and a screen on a stand.

Your Business, Our Space

Meetings & Events

Host your next group event or business meeting at MainStay Suites in Houston’s vibrant Texas Medical Center/Reliant Park district. With a flexible 704 sq ft. boardroom, this space is perfect for professional presentations, celebratory gatherings, brainstorming sessions—or simply socializing over drinks and laughter.

Groups & Events

Top Attractions, Shopping, & Family Fun

Things to Do in Houston

Our MainStay Suites hotel is conveniently located in the heart of Houston, so you can easily access many nearby attractions. To make travel even simpler, we provide free shuttle transportation to the Texas Medical Center and local sites within three miles of the hotel. Our hotel is conveniently located near the Houston Zoo, George R. Brown Convention Center and George Bush Intercontinental Airport.

Area Guide

The image shows an illuminated skate park at night with ramps and bowls, surrounded by trees and pathways in a park setting.
A modern office building with a reflective glass facade and a metallic ring sculpture, set beside a tranquil pond under a clear blue sky.
A city skyline with tall buildings, a river, a bridge, and green spaces under a partly cloudy sky.
A baseball game is taking place at a stadium under a partially cloudy sky, with a large crowd and a scoreboard in the background.

Top Attractions, Shopping, & Family Fun

Things to Do in Houston

Our MainStay Suites hotel is conveniently located in the heart of Houston, so you can easily access many nearby attractions. To make travel even simpler, we provide free shuttle transportation to the Texas Medical Center and local sites within three miles of the hotel. Our hotel is conveniently located near the Houston Zoo, George R. Brown Convention Center and George Bush Intercontinental Airport.

Area Guide

A baseball game is taking place at a stadium under a partially cloudy sky, with a large crowd and a scoreboard in the background.